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Editor Name: Vaishali Kapoor
Designation: Research associate
University: University of Washington
Country: USA
Biography: Vaishali
Kapoor earned her Ph.D from the All India Institute of Medical Sciences, New
Delhi. She is currently a postdoc in the Department of Radiation Oncology,
Washington University in St. Louis School of Medicine. Her research involves
development of novel drug candidates against radiation-inducible neo-antigens.
Radiation treatment induces cell-surface expression of novel intracellular
proteins. Several peptides have been identified and monoclonal antibodies have
been generated against these antigens. Her aim is to identify and characterize a
lead peptide and antibody which can be used for pre-clinical efficacy studies
and then be extended to the clinic. In addition to the drug-discovery research,
she is trying to understand the biological mechanisms involved in development
of radiation-induced lymphopenia. She has successfully developed a mouse-model
for radiation-induced lymphopenia. Using this in vivo model we have shown for the first time that radiation
induces lymphopenia by both direct and indirect effects on the bone marrow stem
cells
Editor Name: Vaishali Kapoor
Designation: Scientist
University: Washington University School of Medicine
Country: India
Biography: Vaishali Kapoor earned her Ph.D from the All India Institute of Medical Sciences, New Delhi. She completed her postdoc in the Department of Radiation Oncology, Washington University in St. Louis School of Medicine. Her research involves development of novel drug candidates against radiation-inducible neo-antigens. Radiation treatment induces cell-surface expression of novel intracellular proteins. Several peptides have been identified and monoclonal antibodies have been generated against these antigens. Her aim is to identify and characterize a lead peptide and antibody which can be used for pre-clinical efficacy studies and then be extended to the clinic. In addition to the drug-discovery research, she is trying to understand the biological mechanisms involved in development of radiation-induced lymphopenia.