Editor Name: Tanyeri Barak
Designation: Research Scientist
University: Yale School of Medicine
Dr. Tanyeri Barak went to medical school in Istanbul Faculty of Medicine. In the last year of my medical education I received one year research scholarship from Yale University and I worked as a research scholar in Murat Gunel`s laboratory at Department of Neurosurgery & Program on Neurogenetics between 2009 and 2010. I was in charge of a major project and successfully discovered the role of LAMC3 and NDE1 in human brain development. This discovery resulted in a first author Nature Genetics publication, which is the most prestigious scientific journal in the field of genetics. I demonstrated that patients suffering from LAMC3 mutations have an isolated occipital cortex developmental abnormality. LAMC3 has been one of the first isolated cortical malformation genes published in the literature. This finding helped us better understand the embryological development of the occipital cortex, the specialized brain area for vision. I also involved in other projects led by other team members and these studies resulted in Nature and American Journal of Human Genetics publications, which were widely cited in original articles and reviews published in high impact journals (529 citations until February 4th 2017).
After graduating from my medical school in Turkey, I re-joined Murat Gunel` laboratory at Yale in 2013 as a postdoctoral fellow. I have been promoted to a research faculty position in 2015. My major contribution has been in intracranial aneurysms genetics, neurodegenerative motor neuron disorders and developing animal models for novel microcephaly candidate genes.
He is additionally working on developing a prediction method for the genes involved in motor neuron disorders such as Amyotrophic Lateral Sclerosis (ALS) or Charcot-Marie-Tooth Disease (CMT) based on the genome.