,,,,,,, Madridge Publishers | Journal of Traditional Medicine and Applications

International Journal of Traditional Medicine and Applications

ISSN: 2689-1638

International Conference on Traditional Medicine and Ethnobotany

September 23-24, 2019 , Kuala Lumpur, Malaysia.
Accepted Abstracts
DOI: 10.18689/2689-1638.a1.004

King of All Fruit: Assessment of Durian Antioxidant and Cytoprotective Properties

Gabriella Tyler

Georgia Gwinnett College, USA

Duriozibethinus (durian) is a thorny shelled, podded pulp bearing fruit indigenous to Southeast Asia. Durian shell and rind have been shown to have antioxidant activity; however, the antioxidant activity of durian pulp has not been examined. In this study, the durian pulp antioxidant activity was evaluated as well as a closely related fruit, Artocarpus heterophyllus (jackfruit). First, TEAC assays were conducted to determine durian and jackfruit antioxidant activity. Next, durian and jackfruit were introduced to PtK-2 cells at a 2.0% concentration (in DMSO) and to determine if these dosages could “rescue” cell death caused by hydrogen peroxide. Initial data supports the hypothesis that both species possess enough antioxidant properties to prevent total cell death cause during the “rescue”. However, the quantitative data suggests that jackfruit is a stronger antioxidant than durian because the population of viable cells within the well treated with jackfruit concentration was significantly higher compared to the durian wells.

Signal Analysis of the Yuan Point in Patients with IBS-Acupoint Diagnosis Technology for Intelligent Acupuncture Robot

Tiancheng Xu

Nanjing University of Chinese Medicine, China

Objective: To explore the law and distribution characteristics of acupoint sensitization among the IBS patients with meridian theory and graph theory, for further understanding of acupoint sensitization in clinical practice.

Methods: For mathematical modeling, achieve the acupoints and their indications of diseases in the classic books of acupuncture and moxibustion. Establish the acupoint-indications network based on the graph theory and record the topological parameters such as clustering coefficient, vector centrality etc. For the clinical trial part, the method of cohort study was adopted to include the patients meeting the diagnostic criteria of IBS and the acupoint sensitivity data was measured through body meridian energy system. The topological indexes obtained by mathematical modeling were introduced to calculate the weighted average of topological parameters of the Yuan point, so as to further analyze its correlation with the disease and compare with the traditional analysis methods.

Results: 1. Acupoint-symptom complex network of acupuncture and moxibustion classic books all show “small world effect”, among which acupoint nodesʼ close centrality and feature vector centrality indexes present acupoint specificity, which can be used as acupoint weight index for weighted average algorithm; 2. The original point resistivity abnormality rate of patients with diarrhea irritable bowel syndrome was 40.71% and that of healthy subjects was 29.49%. The resistance of patients with irritable bowel syndrome was higher than that of healthy subjects; 3. Based on the weighted average algorithm of intermediary centrality or eigenvector centrality, the weighted average of topological parameters of primary point resistance in patients with diarrhea irritable bowel syndrome was higher than that of healthy subjects.

Conclusion: 1. Having “small-world effect” may be one of the topological characteristics of acupoint-symptom complex network; 2. The increase of skin primary point resistance in patients with IBS-D is a manifestation of acupoint sensitization; 3. Acupoint Hegu (LI4) sensitization on behalf of the large intestine meridian is one of the specific manifestations of primary acupoint sensitization in patients with diarrhea irritable bowel syndrome; 4. It is a feasible attempt to study and express the law of acupoint sensitization based on graph theory.

Tiancheng Xu is an innovator in China, the first Chinese ever who got the Nasser Bin Hamad International Youth Creativity Award. He is founder of Acubots which invents an acupuncture robot and recognized by Medical Robotics Society, Microsoft, Takeda, Renesas and entered Top 36 of Lee Kuan Yew Global Business Plan Competition. Tiancheng has got Excellent Volunteer for United Nations “MY World” Actions, 1st prize of NECCS and 136 awards in college. He published 34 academic papers and is also a medical science writer with more than 3,000,000 hits. He was protocol supervisor for the 2nd Asian Youth Games and now a member of the China Young Leaders Exchange Network.

The Relationship between the Spasticity-Related Pain and the Quality of Life about the Cerebral Palsy in China

Zhenhuan Liu1*, Yong Zhao1, Wenjie Fu1, Xuguang Qian1, Chuntao Zhang1, Shangsheng Dong2, Mona L. Martin3, Donald M. Bushnell3, Thorin L. Geister4, Yuqiong Zhang5 and Jie Yang6

1Guangzhou University of Traditional Chinese Medicine, China
2Jiangmen Maternity and Child Health Care, China
3Health Research Associates, USA
4Merz Pharmaceuticals GmbH Eckenheimer, Germany
5Rehabilitation Division MCH Hospital of Dongguan, China
6XiangYaBoAi Rehabilitation Hospitals, China

Purpose: Children and adolescents with cerebral palsy suffered from spastic pain that affected their quality of life. The purpose of this study was to examine the relationship between the spasticity-related pain and the quality of life about the children with cerebral palsy with spasticity-related pain in China.

Methods: This was a prospective, observational, one-arm multicenter study. 137 cerebral palsy children with SRP and their parents/caregivers were recruited from three sites in China. The children and their parents/caregivers completed the Questionnaire on pain caused by Spasticity and PedsQLTM 4 scale.

Results: 137 children with their parents/caregivers were eligible for participation in the study and all completed the relevant investigation. According to the result of the children-report PedsQL, the total scale scores in the V2/V3 about the different age groups (5-7 years old, 8-12 years old, 13-16 years old) had no statistical significance (P>0.05). After 3 weeks, the change compared to first time survey result was not significant (p>0.05). The total scores and each domain of PedsQL in the CP with SRP was lower than the normal group (P<0.05). On the whole, the associations between the child and parent proxy-report QPS total scores and each domain scores of PedsQL were moderate to high. The PedsQL total scores relationship to the QPS item score was moderate.

Conclusion: The quality of life in the CP patients with SRP was worse than normal people and it was a steady long-term stage. The correlation between the spasticity-related pain and the quality of life was moderate to high and negative and the result from the parent proxy-report was more evident.

Therapeutic Activity of HPLC Purified Pure Compound Lantadene D from Lantana camara Leaves against Trypanosomaevansi

Peter Shaba1*, S. Dey1 and Singh R. K2

1College of Agriculture, Nigeria
2Indian Veterinary Research Institute, India

Trypanosomosis, a zoonotic disease is on the increase in recent years. Current limited classes of drugs in used are facing lot of problems. As a result of this Lantana camara leaves, a poisonous leaves were subjected to different stages of purification such as methanolic extraction, column chromatography, rechromatography, thin layer chromatography, preparative thin layer chromatography, High performance liquid chromatography (HPLC) and structure elucidation and lantadene D was obtained. Lantadene D at concentrations (250-1000 µg ml-1) was screened against Trypanosomaevansi on Vero cell line grown in Dulbeccoʼs Modified Eagle Medium (DMEM) (Sigma) in 96-well flat bottom micro culture plates (Nunc, Denmark). Each well received 100 µl of DMEM containing 5x105 cells/ml. The plates were incubated at 37°C under 5% CO2 for 48 hr to complete development of monolayer. After the formation of confluent monolayer, the medium (DMEM) was discarded and replaced with a fresh DMEM. And the medium was supplemented with 20-40% fetal calf serum (FCS), Gibco USA and antibiotics (100 unitʼs penicillin, 100 µg streptomycin and 40 µg gentamycin). A high parasitaemic blood from mouse was diluted with DMEM to obtain final trypanosomes of 1x106 trypanosomes/ml. The suspension (100 ml of medium with trypanosomes) was added at rate of 1:1 to pure compound lantadene D from Lantana camara and the plate was incubated under the same conditions mentioned above. The test was repeated at least thrice. In vitro cytotoxicity was performed on the same medium at concentrations (1.56-100 µg/ml) but without supplement of fetal calf serum in triplicate and incubated under the same conditions described previously. In this research, pure compound lantadene D from Lantana camara showed marked trypanocidal activity with reduction of trypanosomes in corresponding ELISA plate wells at concentration of 250 µg/ml, (40.±0.0 to 4.667±0.3), after 9 hr of incubation. However at 500 µg/ml of lantadene D, trypanosomes were not detectable in ELISA plate wells at 9 hr of incubation. Lantadene D and diminazine aceturate were cytotoxic to Vero cells in all concentrations except at 6.25 µg/ml, respectively. Pure compound Lantadene D from L. camara at the same concentration showed the same level of cytotoxic effects with diminazine aceturate, the reference drug despite toxic nature of the former to animals. Lantadene D displayed significant trypanocidal activity. This may pave way for a nascent drug discovery.

The Clinical and Experimental Study on Acupuncture for Children with Cerebral Palsy

Zhenhuan Liu

Guangzhou University of Traditional Chinese Medicine, China

In this study, 146 cases of brain injury and 1078 cases of cerebral palsy were included by randomized controlled study with ICF (GMFM, Peabody fine motor function, Gesell, muscle tension, joint activity, ADL, TCD, skull B ultrasound, head CT/MRI, SPECT, DTI) evaluation method. The results showed that (1)The recovery rate of extracellular space (92.3%) was significantly higher than that of the control group (70.8%) (P <0.05), TCD total efficiency (79.3%) was significantly higher than that in the control group (51.8%) (P<0.05) acupuncture to promoting the development of neurological and cognitive movement under 6 months children, effectively reduce the neurological sequelae. (2)The total effective rate of the children with cerebral palsy was 87% in the acupuncture group, which was significantly higher than that of the control group (P <0.01). The total effective rate of CT/MRI was 59.55% in the acupuncture group and 13.25% higher than that in the control group (P <0.01). The total effective rate was 91.3% in the 1 year follow-up group, which was significantly higher than that in the control group (P <0.01).

The FA value of white matter fiber bundle was significantly higher than that of acupuncture at 60 times (P <0.05). The recovery rate of ultrasonous brain injury (86.7%) in acupuncture group was significantly higher than that in control group (64.4%) (P<0.05) The recovery rate of SPECT in acupuncture group was 96.4%, which was significantly higher than that in the control group (P<0.01). (3)Acupuncture rehabilitation not only promote the development of white matter and gray matter in children with cerebral palsy, but also promote the brain function of children with cerebral palsy remodeling, compensation and promote social adaptation, language and other cognitive function development, children with cerebral palsy movement and fine motor function development and recovery, improve the childrenʼs self-care ability.

Professor Zhenhuan Liu is the deputy manager of the Affiliated Maternity and Child Care Hospital of Guangzhou University of Traditional Chinese Medicine, the director of the rehabilitation centre for cerebral palsy of the hospital and the master tutor of the Guangzhou University of Traditional Chinese Medicine. Prof. Zhenhuan Liu became one of the pediatricians who received the special state Council allowance in China in 1994, was given the title of the prominent contribute youth expert by the Healthy Ministry of China in 2002. In 2005, Prof. Zhenhuan Liu got the honor of “model worker in nationwide”. In addition, Prof. Zhenhuan Liu is also the adjunct professor of the Hong Kong Medical College of Traditional Chinese Medicine and Pharmacy and the Health Institute of Indonesian Ministry of Health.

The Efficacy of the Psychological Action Rehabilitation on Music Therapy Combined with Acupuncture Therapy for Children with Autism Spectrum Disorder

Zhenhuan Liu

Guangzhou University of Traditional Chinese Medicine, China

Objective: To verify the efficacy of the Psychological Action Rehabilitation on autism treated with Five Elements Music Therapy combined with acupuncture and massage therapy.

Methods: A total of 70 cases with autism spectrum disorder (ASD) were divided into an observation group (30 cases) and a control group (40 cases). In observation group, the cases were treated with Five Elements Music Therapy combined with acupuncture and massage therapy. The control group was treated with structured education. Clancy Autism Behavior Scale Childhood Autism Behavior Scale (CARS) Autism Behavior Checklist (ABC) and Gesell Development Scale (social adaptive behaviors, personal social behaviors and language development) were adopted to assess the scores before and after treatment. The results were analyzed by SPSS13.0 software.

Results: 1) During the same time treatment, the observation groupʼs efficacy on enhancing the intelligence and language ability is apparently better than the control group. 2) In observation, between the group aged from 4 to 6 years and the group aged from 2 to 3 years, the differences in Clancy Autism Behavior Scale, ABC and social adaptive development scale are not obvious, which explains that Five Elements Music Therapy combined with acupuncture and massage therapy can improve autism spectrum disorder childrenʼs behavior and intelligence level regardless of age. 3) As for the scores of language in Gesell scale in the observation group, there were significant differences before and after treatment, which explains that the observation groupʼs therapy can enhance autism spectrum disorder childrenʼs language skill and is better than the control groupʼs therapy.

Conclusion: Five Elements Music Therapy combined with acupuncture and massage therapy can significantly improve the efficacy on autism spectrum disorder, effectively relieve child autism symptoms and enhance the intelligence and language ability.

Professor Zhenhuan Liu is the deputy manager of the Affiliated Maternity and Child Care Hospital of Guangzhou University of Traditional Chinese Medicine, the director of the rehabilitation centre for cerebral palsy of the hospital and the master tutor of the Guangzhou University of Traditional Chinese Medicine. Prof. Liu became one of the pediatricians who received the special state Council allowance in China. In 1994 he was given the title of the prominent contribute youth expert by the Healthy Ministry of China in 2002. In 2005 Prof. Liu got the honor of “model worker in nationwide”. In addition, Prof. Liu is also the adjunct professor of the Hong Kong Medical College of Traditional Chinese Medicine and Pharmacy and the Health Institute of Indonesian Ministry of Health.

Anti-Hepatitis C Virus Activity in Eclipta alba: Identification of Active Phytochemicals

Virendra Pandey

Rutgers University, USA

Chronic hepatitis C virus (HCV) infection is the most common cause of liver cirrhosis and hepatocellular carcinoma and is an early indication for liver transplantation. In a search for Anti-HCV phytochemical, we found that the Eclipta alba extract potently inhibited RNA-dependent RNA polymerase (RdRp) activity (IC50 11 μg/ml) of HCV replicase (NS5B) in-vitro. When the extract was supplemented in a cell culture system, it effectively blocked both HCV RNA replication and translation in MH 14 cells carrying the replicating HCV subgenomic replicon. Bioassay-based fractionation of concentrated crude extract using silica gel and preparative scale reverse-phase HPLC chromatography isolated five compounds that exhibited Anti-HCV activity in a cell culture system. Three of these compounds identified as wedelolactone, leteolin and apigenin, shown dose-dependent in-vitro inhibition of RdRp activity of HCV replicase. In combination, wedelolactone and leteolin synergistically inhibited NS5B RdRp activity in-vitro. These Anti-HCV phytochemicals from Eclipta alba may have therapeutic potential in the treatment of chronic HCV infection and restoration of liver function.

Dr. Virendra Pandey received his Ph.D. in 1985 from the University of Mumbai at Bhabha Atomic Research Center (BARC), India. He served as Professor (Scientist-F) at BARC and received the most prestigious Shanti Swaroop Bhatnagar Award in 1991 for his research contribution in Life Sciences. He has published more than 90 research articles in reputed peer reviewed journals and has received continuous research funding from the National Institute of Health. Currently, he is a tenured senior faculty and a member of the Rutgers University Senate.

War on Terror Cells: Novel Sources of Antimicrobials

Naveed Ahmed Khan1*, Salwa Mansur Ali1, Noor Akbar1, Ruqaiyyah Siddiqui1, Ayaz Anwar2 and Muhammad Raza Shah2

1Sunway University, Malaysia
2University of Karachi, Pakistan

With the worsening trends of drug resistance, there is a need for newer and more powerful antimicrobial agents. The search for new compounds originating from natural resources is a promising research area. We hypothesized that animals living in polluted environments are potential source of novel antimicrobial molecules. Under polluted milieus, organisms such as cockroaches encounter different types of microbes including superbugs. Such creatures survive on slaught of super bugs and are able to ward off disease by producing antimicrobial substances. Here, we characterized antibacterial properties in extracts of various body organs of cockroaches (Periplaneta americana) and showed potent antibacterial activity in crude brain extract against methicillin-resistant Staphylococcus aureus and neuropathogenic E. Coli K1. The size-exclusion spin columns revealed that the active compound(s) are less than 10 kDa in molecular mass. Using cytotoxicity assays, it was observed that pre-treatment of bacteria with lysates inhibited bacteria-mediated host cell cytotoxicity. Using spectra obtained with LC-MS on Agilent 1290 infinity liquid chromatograph, coupled with an Agilent 6460 triple quadruple mass spectrometer, tissues lysates were analyzed. Among hundreds of compounds, only a few homologous compounds were identified that contained isoquinoline group, chromene derivatives, thiazine groups, imidazoles, pyrrole containing analogs, sulfonamides, furanones, flavanones and known to possess broad-spectrum antimicrobial properties and possess anti-inflammatory, anti-tumour and analgesic properties. Further identification, characterization and functional studies using individual compounds can act as a break through in developing novel therapeutics against various pathogens including super bugs.

Naveed Ahmed Khan is Distinguished Professor and Head of the Department of Biological Sciences at Sunway University. Prior to joining Sunway, he has held positions at Tufts University School of Medicine, Boston, USA; Johns Hopkins University School of Medicine, Baltimore, USA; University of London, UK; University of Nottingham, UK andAga Khan University, Pakistan. With research grants of over $2 million, he has produced over 210 peer-reviewed publications, 7 books and 7 chapters and guided over 40 graduate students. In recognition of his research efforts, he has received awards from the UK, USA, Pakistan and Malaysia. His work on the search for new antibiotics from animals living in polluted environments caught worldwide attention where it was discussed in peerreviewed journals and made into documentaries shown on leading news channels.Google search of “Naveed Khan and Cockroach” yields thousands of web pages.

Holistic Fitness Saves the Human Species in a Robotic Era

Julie Rammal

Geroge Washington University, USA

The body is another living organism and it should not be abused, but rather honoured. In todayʼs era the body, mind and spirit have lost connection and are constantly bombarded by external threats. As a result, we see a society that is unhappy, dis-connected, sick and our mental, emotional and physical states are worsening. The human being has forgotten the primitive ways of live, sleep, eat, heal, emotions and a result with the boom in the technological era and external bombardements we are begining to see the death of the human being species. The holistic movement helps human beings adapt to a new era where humans are being human robots. She states that, “Your body is an empire and when you are connected to you, you can achieve miracles. It speaks a language that we are failing to listen to.

Julie shares her advanced training techniques with the public that has helped numerous people find their life, strength through the holistic approach. She shares the exercises that are the future of movement and her secret tools to scan the body such as the body scan, eye and image projection methodologies, hand and color therapy and more. Through her work, clients have experienced immediate relief from various pains have healed and experienced a change in their emotional state. Holistic fitness is the future of movement and medicine is the only training metholody that will keep human beings stay connected to themselves in an era where we are evolving to become robotic.

Julie Rammal founder of JSport and the holistic fitness movement, International Holistic Trainer, Speaker & Influencer, writer, consultant and founder of the worldʼs first holistic fitness dvd: In Light of Change. She has inspired thousands worldwide on the power of holistic fitness. Having trained numerous VIP & celebrities, corporations, embassies, resorts she is widely known for her holistic approach towards understanding, communicating and assisting the body and mind in just three energy-fuelled sessions. Her work has been published in: Yahoo Finance, Khaleej Times, Gulf times, USA press and seen on MTV, Future TV, NBN and multiple more press worldwide.

Alternative Medicine: Doubtful Treatment or a Powerful Healing Force

Roger Haw Boon Hong

International Council of Electrohomeopathy, Malaysia

Alternative medicine is an approach to healing used in place of conventional medicine. Complementary medicine, on the other hand, is used together with conventional medicine. For example, if a special diet is used to treat cancer in place of surgery recommended by a conventional doctor, the diet would serve as an alternative therapy. However, if a special diet were used to combat high cholesterol levels in a patient with heart disease, in addition to coronary artery bypass surgery, the diet would serve as a complementary therapy. Since the same therapy can serve as either complementary or alternative, the various therapies outside the domain of conventional medicine are often grouped together under the term CAM (complementary and alternative medicine) therapies. The increasing interest in alternative medicine, which attempts to treat a patientʼs body, mind and spirit can be viewed as a measure of the spiritual hunger in our high-tech society. The desire within the medical community to integrate treatments for a patientʼs spiritual needs as well as physical needs is validating the importance of pastoral care in the hospital setting. Perhaps an approach to healing that makes use of the strengths of both conventional medicine and alternative medicine would enable a person to experience the best of both medical worlds. The forms of alternative medicine with scientific backing could be used to maintain health and increase physical fitness, while conventional medicine could be used to accurately diagnose and eradicate disease. Certain cautions, however, should be observed.

Professor Dr. Roger Haw Boon Hong is an Executive Director for Education (1) International Council of Electrohomeopathy and (2) American Nutritional Medical Association for Malaysia Chapter. Major ranking position serves at Malaysia Civil Defence Force. Co-Founder of Ansted University and Visiting Professor for various Universities in the field of Humanities, Community Development, Corporate Social Responsibility, Environmental and Sustainable Development Sciences, Strategic Management, International Marketing, Cultural Arts, Distance Education and Peace Education.

The Use of Blood Cupping Therapy in Reducing Cardiovascular Disease Risk Factors

Ab Aziz al-Safi bin Ismail

Lincoln University College, Malaysia

Blood cupping therapy is a form of complementary medicine practiced by extracting the blood that is believed to be harmful from the body. Ninety three subjects aged between 30 and 60 years old participated in the study aims to determine the effect of blood cupping therapy on health. Sixty two on diabetic individual without chronic disease were randomly and equally assigned into control and intervention group. For diabetic group, 31 subjects were included. Blood cupping were done on subjects in the intervention and diabetic group, whereas individual in the control group were remained untreated. Assessments were done at baseline, first month, third month (before the second session of cupping) and fourth month for all participants.

Results: In non diabetic and diabetic cupping group, there were significant reductions in fasting blood sugar (FBS) and all renal function parameters from baseline to the first, third and fourth month. The von Willebrand factor (VWF) antigen also showed significant reduction at fourth month. At the end of the study, all the serum lipid profiles, FBS, serum urea and creatinine in cupping group were significantly differ as compared with control group. For serum HDL-C and LDL-C, the significant difference between cupping and control group were seen at the third and fourth month.

Conclusions: Wet cupping therapy showed significant improvement in blood pressure and certain component of biochemical parameters, renal function parameters and also endothelial functions. Therefore, wet cupping could contribute in reducing and preventing the risk factors for cardiovascular disease.

Dr Ab Aziz al-Safi bin Ismail (MD, PhD) is a professor of public health at Lincoln University College, Kota Bharu campus who specializes in diabetes mellitus, metabolic syndrome and malignancies. He is practicing integrative and functional medicine and actively involved in conducting clinical trials and epidemiological research. Recently, he conducted a study on the use of blood cupping in reducing cardiovascular disease and actively speaks on treating chronic diseases using blood cupping therapy.

Phytopharmaceuticals: An Emerging Platform in Modern Medicine

Dilip Ghosh

Nutriconnect, Australia

A comprehensive review to be presented which shows the plant kingdom as an almost inexhaustible reservoir of potential drugs. The longstanding, successful use of herbal drug combinations in traditional medicine makes it necessary to find a rationale for the pharmacological and therapeutic superiority of many of them in comparison to isolated single constituents. As a result, a new category “Phytopharmaceutical” has emerged in several countries. There are many definitions but the core essence is “Phytopharmaceutical drug includes purified and standardized fraction with defined minimum four bio-active or phytochemical compounds (qualitatively and quantitatively assessed) of an extract of a medicinal plant or its part, for internal or external use of human beings or animals for diagnosis, treatment, mitigation or prevention of any disease or disorder but does not include administration by parental route” (CDSCO, Govt of India, 2016). In last decade we have seen the sluggish growth of Herbal/Ayurvedic products and decrease in Pharma R&D output in terms of reduction in number of NCEs and increasing cost of new drug discovery. Current allopathic practice is unable to meet the unmet needs of multicomponent drug for multi target diseases. A number of problems, such as usefulness of RCTs in herbal medicine which are connected with the search for new prototype drugs of biological origin are also described. Special attention will be given on role of natural products in therapy; as biologically active compounds as such, as starting materials for (semi)synthetic drugs and also as source of inspiration or as models for the synthesis of new drugs with better therapeutic, chemical or physical properties than the original compounds.

Dilip has received his PhD from India. He is an international speaker, facilitator and author and professionally associated with Nutriconnect, Australia; Honorary Ambassador, Global Harmonization Initiatives (GHI) & adjunct-Industry Fellow, NICM, Western Sydney University. He is a fellow of American College of Nutrition (ACN), professional member of Australian Institute of Food Science & Technology (AIFST), an advisor and executive board member of Health Foods and Dietary Supplements Association (HADSA), India and also in editorial board of several journals.
Dr. Ghosh has published more than 100 papers in peer reviewed journals, numerous articles in food and nutrition magazines and books. His most recent book, “Pharmaceuticals to Nutraceuticals: A shift in disease prevention” under CRC Press, USA has been published in 2016.

Need of the Decade-Studies on Line of Treatment and Underlying Mechanism of Cam for Type 2 Diabetes

Ong Pei Jia* and S. Tripathi

Union Yoga Ayurveda, Singapore

Type 2 Diabetes Mellitus (T2DM), the seventh leading cause of death, is a biggest challenge for mankind. Despite of fascinating advances in pharmaco-therapeutic agents, the prevalence of T2DM is growing every year. Complementary and Alternative medicine (CAM) as classified by National centre of CAM have documented various positive results of T2DM. Whole ancient medical systems like Ayurveda, Siddha and TCM etc use natural herbs either as a single drug therapy or in the form of formulations, depending upon principles of respective medical system. Studies done on various herbs and mind body intervention like yoga, acupuncture etc are found to be beneficial for T2DM. This resulted, large number of physicians either referring to or practicing some of the more prominent and well known forms of CAM.

The concepts proposed and used by these CAM systems (that are kept alive by CAM practitioners for thousands of years) appear very mysterious to the present day biomedical practitioners. These models of therapies seem to have evolved through several phases of internal research just like the present day drug trials that go through 4 phases of intensive statistical evaluation. It appears that todayʼs scientists need to follow the footsteps of research used by the ancient seers of TCM, Ayurveda, Siddha, Yoga or Homeopathy to unravel these mysterious theories.

This review talks about generating evidence not only for the efficacy of these holistic systems but also in carrying out systematic research by biomedical scientist who have the knowledge of both the western and eastern sciences.

Ayurveda for Heart Diseases-An Overview

Mridu Sharma

Smt. Urmila Devi Ayurvedic College, India

Heart, Brain and Kidney are considered the most vital part of our body. Disease to any of these organ is life threatening. Heart disease is the leading cause of death in both men and women and besides that it is also found in almost all type of ethnicities of the world. Coronary heart disease (CHD) is the most common of all type of heart diseases killing about 3,70,000 people every year. The main risk factors of heart diseases are high blood pressure, high cholesterol and smoking. Some medical and lifestyle conditions like Diabetes mellitus, Obesity, alcohol consumption also increase the risk of heart diseases. Heart disease in Ayurveda is known as “Hridroga”.

According to Ayurveda heart disease are of five types according to predominance of doshas i.e. Vataj (Vata Predominence), Pittajn (Pitta predominance), Kaphaj (kapha predominance), Sannipataj (three dosha involvement) and krimij (infestation of worms). As far as treatment is concerned modern can offer medication or surgeries according to condition of the patient which is both risky as well as costly. Ayurveda offers a non-surgical procedure in the form of lifestyle changes, Ayurvedic herbs like Arjun, Sthira and Panchkarma like Hrid Basti, Virechan which can help in the treatment of heart disease as well as risk associated with it.

Dr. Mridu Sharma has completed her M.D. in Panchkarma at the age of 25 years. She is Assistant Professor of Panchkarma at Smt. Urmila devi Ayurvedic College, Hoshiarpur. She has published more than 15 papers in reputed journals and has attended more than 20 national and international conferences. She is practicingAyurveda and Panchkarma since 2014 in her own clinic. She has presented herself as Speaker in 10th International TCM,Ayurveda &Acupuncture Conference held in Berlin on 4th & 5th March 2019.

Naturopathy & Massage Therapy

Prakash Kondekar

Indian Institute of Naturopathy, India

Naturopathy is an art & science of non-invasive healthcare & health assessment in which neither drugs nor surgery are used. Emphasis is given on five elements of Nature like Air, Water, Earth, Ether and Sunlight. Also the help of natural substances like fruits and Vegetables or their juices is taken for Eliminative, Curative and Preventive diets. Naturopathy believes that healing comes from within & body is capable of healing itself. Body Massage is playing a major role for toning of body muscles. Hippocrates, the father of Modern Medicine, formulated the basic Naturopathy concept. Naturopathy is first & foremost preventive system of medicine. Fruits and vegetables is one of the tried & true recommendations for a healthy diet. Eating plenty of fruits & vegetables can help you ward off stress, control blood pressure & cholesterol, prevent some types of cancer, avoid a painful intestinal ailment called diverticulitis.

Body Massage-Our body is made up of flesh & bone, as well as spirit, all interconnected with the integrated & unifying brain & nervous system. The nervous system, structurally an elongation of the brain itself, extends from the base of the skull, through the vertebral canal & the openings of the vertebrae of the backbone, finally penetrating every gland, organ, muscle, bone & tissue, ending in the cells in remotest & deepest parts of our body, as well as our fingertips, toes & skin. Any muscles are tense; there is inevitably a reaction in greater or lesser degree, upon the entire nervous system. Thus Naturopathy and Massage play important role for healthy Body, Mind and Spirit.

Dr. Prakash Kondekar currently is Director of Indian Institute of Naturopathy, India. He had conducted 18 Workshops, Health Management in UK, USA, Germany, Mauritius, Singapore, UAE, Vietnam, Austria, Italy & India. He is faculty member of Food Laws, Science, Microbiology departments in Mumbai & Saurashtra University.