Madridge Journal of Nanotechnology & Nanoscience

ISSN: 2638-2075

International Nanotechnology Conference & Expo
April 04-06, 2016 | Baltimore, USA

Trapping and analyzing particles with Optofluidicsʼ NanoTweezer

Xiangning Li, Thomas Castner, Colby Ashcroft, Jack Zhang, Brian DiPaolo, Noah Alessi, Bernardo Cordovez, Christopher Earhart and Robert Hart

Optofluidics, Inc., USA

DOI: 10.18689/2638-2075.a1.002

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We present the marketʼs latest particle analysis system. The NanoTweezer Surface uses cutting edge nanophotonics and microfluidics to analyze nanoscale particles in solution, chiefly characterizing their size and their surface properties, simply not possible with current instrumentation. The device uses near field optics to impart optical forces that drive the particles to interact against a reference surface, and by measuring the amount of light these particles scatter, the NanoTweezer Surface characterizes the interaction potential to infers the surface properties of the particle. Researchers are using our tool in nanomedicine and nanotoxicity to measure weak and non-ionic interactions such as those imparted when a particle is PEGylated, as well as assess ligand coverage during surface functionalization. The system allows researchers to better assess formulation stability, particle surface coverage and offers key new insights to make better colloidal systems. We will dive into the device physics as well as offer case studies.

Biography:
Ms. Li is technical sales and marketing lead at Optofluidics. She earned 2 Masterʼs Degree (Materials Science & Electrical Engineering) from UPenn and her Bachelorʼs Degree of Materials Science from Tsinghua University.