Madridge
Journal of Analytical Sciences and Instrumentation

ISSN: 2638-1532

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Vibrational Decahertz (daHz), Hectohertz (hHz), Kilohertz (kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation

Alireza Heidari*

Faculty of Chemistry, California South University, USA

*Corresponding author: Alireza Heidari, California South University, 14731 Comet St. Irvine, CA 92604, USA, Email: Scholar.Researcher.Scientist@gmail.com, Alireza.Heidari@calsu.us;

Received: November 02, 2017 Accepted: November 20, 2017 Published: November 25, 2017

Citation: Heidari A. Vibrational Decahertz (daHz), Hectohertz (hHz), Kilohertz (kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. Madridge J Anal Sci Instrum. 2017; 2(1): 41-46. doi: 10.18689/mjai-1000109

Copyright: © 2017 The Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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In the current study, we have experimentally and computationally presented vibrational decahertz (daHz), hectohertz (hHz), kilohertz (kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) imaging and spectroscopy comparative study on malignant and benign human cancer cells and tissues with the passing of time under synchrotron radiation using Mathematica [1-101]. In this regard, first, we have experimentally investigated and compared malignant human cancer cells and tissues before and after irradiating of synchrotron radiation using vibrational decahertz (daHz), hectohertz (hHz), kilohertz (kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) imaging and spectroscopy. It is clear that malignant human cancer cells and tissues have gradually transformed to benign human cancer cells and tissues under synchrotron radiation with the passing of time (Figure 1) [1-101].

Figure 1. Vibrational decahertz (daHz), hectohertz (hHz), kilohertz (kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) spectra of malignant human cancer cells and tissues (a) before irradiating of synchrotron radiation, after (b) 10 days, (c) 20 days and (d) 30 dyas irradiating of synchrotron radiation [1-101].

Furthermore, we have computationally simulated this transformation process according to the passing of time as mentioned above for human cancer cells and tissues (Figures 2 and 3) and also distribution of human cancer cells and tissues (Figures 4 and 5) under synchrotron radiation using Mathematica, respectively [1-101].

Figure 2. Simulation of transformation process of malignant human cancer cells to benign human cancer cells under synchrotron radiation with the passing of time using Mathematica [1-101].
Figure 3. Simulation of transformation process of malignant human cancer tissues to benign human cancer tissues under synchrotron radiation with the passing of time using Mathematica [1-101].
Figure 4. Simulation of transformation process of malignant human cancer cells to benign human cancer cells under synchrotron radiation accroding to the distribution of human cancer cells using Mathematica [1-101]
Figure 5. Simulation of transformation process of malignant human cancer tissues to benign human cancer tissues under synchrotron radiation accroding to the distribution of human cancer tissues using Mathematica [1-101].

In addition, we have comparatively studied vibrational decahertz (daHz), hectohertz (hHz), kilohertz (kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) spectra of malignant and benign human cancer cells and tissues under synchrotron radiation with the passing of time as mentioned before on one coordinate system, respectively (Figures 6 and 7) [1-101].

Figure 6. Vibrational decahertz (daHz), hectohertz (hHz), kilohertz (kHz), Megahertz (MHz),

Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) spectra of malignant and benign human cancer cells under synchrotron radiation with the passing of time on one coordinate system [1-101].

Figure 7. Vibrational decahertz (daHz), hectohertz (hHz), kilohertz (kHz), Megahertz (MHz)

Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) spectra of malignant and benign human cancer tissues under synchrotron radiation with the passing of time on one coordinate system [1-101].

References

  1. Heidari A, Brown C. Study of Composition and Morphology of Cadmium Oxide (CdO)Nanoparticles for Eliminating Cancer Cells. Journal of Nanomedicine Research. 2015; 2(5): 1-20.
  2. Heidari A, Brown C. Study of Surface Morphological, Phytochemical and Structural Characteristics of Rhodium (III) Oxide (Rh2O3) Nanoparticles. International Journal of Pharmacology. Phytochemistry and Ethnomedicine. 2015; 1: 15-19. doi: 10.18052/www.scipress.com/IJPPE.1.15
  3. Heidari A. A Thermodynamic Study on Hydration and Dehydration of DNA and RNA-Amphiphile Complexes. J Bioeng Biomed Sci S. 2016; 006. doi: 10.4172/2155-9538.S3-006
  4. Heidari A. Manufacturing Process of Solar Cells Using Cadmium Oxide (CdO) and Rhodium (III) Oxide (Rh2O3) Nanoparticles. J Biotechnol Biomater. 2016; 6: e125. doi: 10.4172/2155-952X.1000e125
  5. Heidari A. Anti-Cancer Effect of UV Irradiation at Presence of Cadmium Oxide (CdO) Nanoparticles on DNA of Cancer Cells: A Photodynamic Therapy Study. Arch Cancer Res. 2016; 4: 1.
  6. Heidari A. Biospectroscopic Study on Multi-Component Reactions (MCRs) in Two A-Type and B-Type Conformations of Nucleic Acids to Determine Ligand Binding Modes, Binding Constant and Stability of Nucleic Acids in Cadmium Oxide (CdO) Nanoparticles-Nucleic Acids Complexes as AntiCancer Drugs. Arch Cancer Res. 2016; 4: 2.
  7. Heidari A. Simulation of Temperature Distribution of DNA/RNA of Human Cancer Cells Using Time-Dependent Bio-Heat Equation and Nd: YAG Lasers. Arch Cancer Res. 2016; 4: 2.
  8. Heidari A. Quantitative Structure-Activity Relationship (QSAR) Approximation for Cadmium Oxide (CdO) and Rhodium (III) Oxide (Rh2O3) Nanoparticles as Anti-Cancer Drugs for the Catalytic Formation of Proviral DNA from Viral RNA Using Multiple Linear and Non-Linear Correlation Approach. Ann Clin Lab Res. 2016; 4: 1.
  9. Heidari A. A Combined Computational and QM/MM Molecular Dynamics Study on Boron Nitride Nanotubes (BNNTs), Amorphous Boron Nitride Nanotubes (a-BNNTs) and Hexagonal Boron Nitride Nanotubes (h-BNNTs) as Hydrogen Storage. Struct Chem Crystallogr Commun. 2016; 2: 1.
  10. Heidari A. Determination of Ratio and Stability Constant of DNA/RNA in Human Cancer Cells and Cadmium Oxide (CdO) Nanoparticles Complexes Using Analytical Electrochemical and Spectroscopic Techniques. Insights Anal Electrochem. 2016; 2: 1.
  11. Heidari A. Combined Theoretical and Computational Study of the Belousov-Zhabotinsky Chaotic Reaction and Curtius Rearrangement for Synthesis of Mechlorethamine, Cisplatin, Streptozotocin, Cyclophosphamide, Melphalan, Busulphan and BCNU as Anti-Cancer Drugs. Insights Med Phys. 2016; 1: 2.
  12. Heidari A. A Translational Biomedical Approach to Structural Arrangement of Amino Acids′ Complexes: A Combined Theoretical and Computational Study. Transl Biomed. 2016; 7: 2.
  13. Heidari A. Nitrogen, Oxygen, Phosphorus and Sulphur Heterocyclic Anti-Cancer Nano Drugs Separation in the Supercritical Fluid of Ozone (O) Using Soave-Redlich-Kwong (SRK) and Pang-Robinson (PR) Equations. Electronic J Biol. 2016; 12: 4.
  14. Heidari A. An Analytical and Computational Infrared Spectroscopic Review of Vibrational Modes in Nucleic Acids. Austin J Anal Pharm Chem. 2016; 3(1): 1058.
  15. Heidari A, Brown C. Phase, Composition and Morphology Study and Analysis of Os-Pd/HfC Nanocomposites. Nano Res Appl. 2016; 2: 1.
  16. Heidari A, Brown C. Vibrational Spectroscopic Study of Intensities and Shifts of Symmetric Vibration Modes of Ozone Diluted by Cumene. International Journal of Advanced Chemistry. 2016; 4(1): 5-9. doi: 10.14419/ ijac.v4i1.6080
  17. Heidari A. Study of the Role of Anti-Cancer Molecules with Different Sizes for Decreasing Corresponding Bulk Tumor Multiple Organs or Tissues. Arch Can Res. 2016; 4: 2.
  18. Heidari A. Biotranslational Medical and Biospectroscopic Studies of Cadmium Oxide (CdO) Nanoparticles-DNA/RNA Straight and Cycle Chain Complexes as Potent Anti-Viral, Anti-Tumor and Anti-Microbial Drugs: A Clinical Approach. Transl Biomed. 2016; 7: 2.
  19. Heidari A. A Comparative Study on Simultaneous Determination and Separation of Adsorbed Cadmium Oxide (CdO) Nanoparticles on DNA/ RNA of Human Cancer Cells Using Biospectroscopic Techniques and Dielectrophoresis (DEP) Method. Arch Can Res. 2016; 4: 2.
  20. Heidari A. Synthesis, Characterization and Biospectroscopic Studies of Cadmium Oxide (CdO) Nanoparticles-Nucleic Acids Complexes Absence of Soluble Polymer as a Protective Agent Using Nucleic Acids Condensation and Solution Reduction Method. J Nanosci Curr Res. 2016; 1: e101.
  21. Heidari A. Coplanarity and Collinearity of 4′-Dinonyl-2,2′-Bithiazole in One Domain of Bleomycin and Pingyangmycin to be Responsible for Binding of Cadmium Oxide (CdO) Nanoparticles to DNA/RNA Bidentate Ligands as Anti-Tumor Nano Drug. Int J Drug Dev & Res. 2016; 8: 007-008.
  22. Heidari A. Nanotechnology in Preparation of Semipermeable Polymers. J Adv Chem Eng. 2016; 6: 157.
  23. Heidari A. DNA/RNA Fragmentation and Cytolysis in Human Cancer Cells Treated with Diphthamide Nano Particles Derivatives. Biomedical Data Mining. 2016; 5: e102. doi: 10.4172/2090-4924.1000e102
  24. Heidari A. A Successful Strategy for the Prediction of Solubility in the Construction of Quantitative Structure-Activity Relationship (QSAR) and Quantitative Structure-Property Relationship (QSPR) under Synchrotron Radiations Using Genetic Function Approximation (GFA) Algorithm. J Mol Biol Biotechnol. 2016; 1: 1.
  25. Heidari A. The Impact of High Resolution Imaging on Diagnosis. Int J Clin Med Imaging. 2016; 3: 1000e101.
  26. Heidari A. A Comparative Study of Conformational Behavior of Isotretinoin (13-Cis Retinoic Acid) and Tretinoin (All-Trans Retinoic Acid (ATRA)) Nano Particles as Anti-Cancer Nano Drugs under Synchrotron Radiations Using Hartree-Fock (HF) and Density Functional Theory (DFT) Methods. Insights in Biomed. 2016; 1: 2.
  27. Heidari A. Advances in Logic, Operations and Computational Mathematics. J Appl Computat Math. 2016; 5: e144. doi: 10.4172/2168-9679.1000e144
  28. Heidari A. Mathematical Equations in Predicting Physical Behavior. J Appl Computat Math. 2016; 5: e145. doi: 10.4172/2168-9679.1000e145
  29. Heidari A. Chemotherapy a Last Resort for Cancer Treatment. Chemo Open Access. 2016; 5: 4. doi: 10.4172/2167-7700.1000e130
  30. Heidari A. Yoctosecond Quantitative Structure-Activity Relationship (QSAR) and Quantitative Structure-Property Relationship (QSPR) under Synchrotron Radiations Studies for Prediction of Solubility of Anti-Cancer Nano Drugs in Aqueous Solutions Using Genetic Function Approximation (GFA) Algorithm. Insight Pharm Res. 2016; 1: 1.
  31. Heidari A. Cancer Risk Prediction and Assessment in Human Cells under Synchrotron Radiations Using Quantitative Structure Activity Relationship (QSAR) and Quantitative Structure Properties Relationship (QSPR) Studies. Int J Clin Med Imaging. 2016; 3: 516.
  32. Heidari A. A Novel Approach to Biology. Electronic J Biol. 2016; 12: 3.
  33. Heidari A. Innovative Biomedical Equipment′s for Diagnosis and Treatment. J Bioengineer & Biomedical Sci. 2016; 6: e123. doi: 10.4172/2155-9538.1000e125
  34. Heidari A. Integrating Precision Cancer Medicine into Healthcare, Medicare Reimbursement Changes and the Practice of Oncology: Trends in Oncology Medicine and Practices. J Oncol Med & Pract. 2016; 1: 2.
  35. Heidari A. Electronic Coupling among the Five Nanomolecules Shuts Down Quantum Tunneling in the Presence and Absence of an Applied Magnetic Field for Indication of the Dimer or other Provide Different Influences on the Magnetic Behavior of Single Molecular Magnets (SMMs) as Qubits for Quantum Computing. Glob J Res Rev. 2017; 4: 2.
  36. Heidari A. Study of Synthesis, Pharmacokinetics, Pharmacodynamics, Dosing, Stability, Safety and Efficacy of Olympiadane Nanomolecules as Agent for Cancer Enzymotherapy, Immunotherapy, Chemotherapy, Radiotherapy, Hormone Therapy and Targeted Therapy under Synchrotorn Radiation. J Dev Drugs. 2017; 6: e154.
  37. Heidari A. Opinion on Computational Fluid Dynamics (CFD) Technique. Fluid Mech Open Acc. 2017; 4: 157. doi: 10.4172/2476-2296.1000157
  38. Heidari A. Concurrent Diagnosis of Oncology Influence Outcomes in Emergency General Surgery for Colorectal Cancer and Multiple Sclerosis (MS) Treatment Using Magnetic Resonance Imaging (MRI) and Au329(SR)84, Au329-xAgx(SR)84, Au144(SR)60, Au68(SR)36, Au30(SR)18, Au102(SPh)44, Au38(SPh)24, Au38(SC2H4Ph)24, Au21S(SAdm)15, Au36(pMBA)24 and Au25(pMBA)18 Nano Clusters. J Surgery Emerg Med. 2017; 1: 21.
  39. Heidari A. Nanomedicine-Based Combination Anti-Cancer Therapy between Nucleic Acids and Anti-Cancer Nano Drugs in Covalent Nano Drugs Delivery Systems for Selective Imaging and Treatment of Human Brain Tumors Using Hyaluronic Acid, Alguronic Acid and Sodium Hyaluronate as Anti-Cancer Nano Drugs and Nucleic Acids Delivery under Synchrotron Radiation. Am J Drug Deliv. 2017; 5: 2.
  40. Heidari A. Clinical Trials of Dendritic Cell Therapies for Cancer Exposing Vulnerabilities in Human Cancer Cells′ Metabolism and Metabolomics: New Discoveries, Unique Features Inform New Therapeutic Opportunities, Biotech′s Bumpy Road to the Market and Elucidating the Biochemical Programs that Support Cancer Initiation and Progression. J Biol Med Science. 2017; 1: e103.
  41. Heidari A. Integrative Approach to Biological Networks for Emerging Roles of Proteomics, Genomics and Transcriptomics in the Discovery and Validation of Human Colorectal Cancer Biomarkers from DNA/RNA Sequencing Data under Synchrotron Radiation. Transcriptomics 5. 2017; 13: e117.
  42. Heidari A. Elimination of the Heavy Metals Toxicity and Diseases in Disruption of Extracellular Matrix (ECM) Proteins and Cell Adhesion Intelligent Nanomolecules Adjustment in Cancer Metastases Using Metalloenzymes and under Synchrotron Radiation. Lett Health Biol Sci. 2017; 2(2): 1-4.
  43. Heidari A. Sedative, Analgesic and Ultrasound-Mediated Gastrointestinal Nano Drugs Delivery for Gastrointestinal Endoscopic Procedure, Nano Drug-Induced Gastrointestinal Disorders and Nano Drug Treatment of Gastric Acidity. Res Rep Gastroenterol. 2017; 1: 1.
  44. Gobato R, Heidari A. Calculations Using Quantum Chemistry for Inorganic Molecule Simulation BeLi2SeSi”. American Journal of Quantum Chemistry and Molecular Spectroscopy. 2017; 2(3): 37-46. doi: 10.11648/j. ajqcms.20170203.12
  45. Heidari A. Different High-Resolution Simulations of Medical, Medicinal, Clinical, Pharmaceutical and Therapeutics Oncology of Human Lung Cancer Translational Anti-Cancer Nano Drugs Delivery Treatment Process under Synchrotron and X-Ray Radiations. J Med Oncol. 2017; 1(1): 1.
  46. Heidari A. A Modern Ethnomedicinal Technique for Transformation, Prevention and Treatment of Human Malignant Gliomas Tumors into Human Benign Gliomas Tumors under Synchrotron Radiation. Am J Ethnomed. 2017; 4(1): 10.
  47. Heidari A. An Investigation of the Role of DNA as Molecular Computers: A Computational Study on the Hamiltonian Path Problem. International Journal of Scientific & Engineering Research. 2014; 5(1): 1884-1889.
  48. Heidari A. Active Targeted Nanoparticles for Anti-Cancer Nano Drugs Delivery across the Blood-Brain Barrier for Human Brain Cancer Treatment, Multiple Sclerosis (MS) and Alzheimer′s Diseases Using Chemical Modifications of Anti-Cancer Nano Drugs or Drug-Nanoparticles through Zika Virus (ZIKV) Nanocarriers under Synchrotron Radiation. J Med Chem Toxicol. 2017; 2(2): 90-94.
  49. Heidari A. Investigation of Medical, Medicinal, Clinical and Pharmaceutical Applications of Estradiol, Mestranol (Norlutin), Norethindrone (NET), Norethisterone Acetate (NETA), Norethisterone Enanthate (NETE) and Testosterone Nanoparticles as Biological Imaging, Cell Labeling, Anti-Microbial Agents and Anti-Cancer Nano Drugs in Nanomedicines Based Drug Delivery Systems for Anti-Cancer Targeting and Treatment. Parana Journal of Science and Education (PJSE). 2017; 3(4): 10-19.
  50. Heidari A. A Comparative Computational and Experimental Study on Different Vibrational Biospectroscopy Methods, Techniques and Applications for Human Cancer Cells in Tumor Tissues Simulation, Modeling, Research, Diagnosis and Treatment. Open J Anal Bioanal Chem. 2017; 1(1): 014-020.
  51. Heidari A. Modern Approaches in Designing Ferritin, Ferritin Light Chain, Transferrin, Beta-2 Transferrin and Bacterioferritin-Based Anti-Cancer Nano Drugs Encapsulating Nanosphere as DNA-Binding Proteins from Starved Cells (DPS). Mod Appro Drug Des. 2017; 1(1): 000504.
  52. Heidari A, Brown C. Combinatorial Therapeutic Approaches to DNA/RNA and Benzylpenicillin (Penicillin G), Fluoxetine Hydrochloride (Prozac and Sarafem), Propofol (Diprivan), Acetylsalicylic Acid (ASA) (Aspirin), Naproxen Sodium (Aleve and Naprosyn) and Dextromethamphetamine Nanocapsules with Surface Conjugated DNA/RNA to Targeted Nano Drugs for Enhanced Anti-Cancer Efficacy and Targeted Cancer Therapy Using Nano Drugs Delivery Systems. Ann Adv Chem. 2017; 1(2): 061-069.
  53. Heidari A. Vibrational Spectroscopy of Nucleic Acids. Wahid Ali Khan (Editor). “Basic Biochemistry”. Austin Publishing Group (APG)/Austin Publications. P1- P18, Jersey City, New Jersey, USA, 2016.
  54. Heidari A. High-Resolution Simulations of Human Brain Cancer Translational Nano Drugs Delivery Treatment Process under Synchrotron Radiation. J Transl Res. 2017; 1(1): 1-3.
  55. Heidari A. Investigation of Anti-Cancer Nano Drugs′ Effects′ Trend on Human Pancreas Cancer Cells and Tissues Prevention, Diagnosis and Treatment Process under Synchrotron and X-Ray Radiations with the Passage of Time Using Mathematica. Current Trends Anal Bioanal Chem. 2017; 1(1): 36-41.